Another Award for Bausch+Ströbel

Bausch+Ströbel has won the Technology Excellence Award in the "Pharmaceuticals/Medical Device" category

The special machine manufacturer located at Ilshofen/Germany can look back on a long and successful story of innovations. Since quite some time, Bausch+Ströbel has been taking an entirely new approach to external cleaning of vials and other packaging materials. Instead of the usual mix of water and cleaning solution, a new CO2 Snow Jet Cleaning process is now used for cleaning the exterior of containers. For this technology Bausch+Ströbel has won the Technology Excellence Award in the "Pharmaceuticals/Medical Dvice" category on the Pack Expo show in Chicago, the leading pharmaceutical exhibition in the United States.
 
This new process turned out to be convincing to the international trade visitors who took part in the online-vote for the Pack Expo awards.
 
CO2 Snow Jet Cleaning systems use solid CO2 ice crystals as a jet medium. With its combination of mechanical, thermal and chemical properties, CO2 snow is able to gently detach and remove a whole variety of surface contamination.
 
This offers huge advantages over the conventional cleaning method: The disposal of the CO2 is especially friendly to the environment. Water-based cleaning methods consume 500 to 1000 liters of water per hour. Disposal of the water used for removing highly active or toxic substances from the outer surface of containers is complicated and expensive. In addition to reduced waste disposal, this also means less expenditure on safety measures for the pharmaceutical customers.
 
Cleaning with this new method is much more efficient, especially when it comes to removing toxic or highly active substances.
 
Detailed description of the process:
The CO2 snow jet cleaning process utilizes liquid carbon dioxide, which is discharged from a two-component nozzle and expands under atmospheric pressure to form ice crystals (solidification). These crystals impinge at high velocity on the surface of the material to be cleaned, where they change from a solid state to a gaseous state (sublimation).
 
This process is non-abrasive and, therefore, does not alter the surface structure of the container being cleaned.
Developed at the Fraunhofer IPA in Stuttgart, Germany, the sublimation-impulse technique is the most efficient process to date for cleaning with CO2 snow worldwide.
 
For instance, it is a very efficient way of removing adherent particles from the outer surface of containers after the lyophilization process, but before labeling.
It also has benefits when used upstream from particle testing stations: removing particles from the glass outer walls of containers means far fewer false alarms due to misidentification of exterior particles as interior particles.
 
CO2 Snow Jet Cleaning produces better cleaning results than water-based methods, and there is no risk of liquid collecting under the flip-off caps of vials. Moreover, there is no need for the drying process otherwise necessary after cleaning containers with water.
 
Further benefits include waste reduction. Water-based cleaning methods consume 500 to 1000 liters of water per hour. Disposal of the water used for removing highly active or toxic substances from the outer surface of containers is complicated and expensive. In the CO2 Snow Jet Cleaning process the CO2 is simply extracted together with the separated particles and filtered. The only part which needs replacing is the filter.
 
In addition to reduced waste disposal, this also means less expenditure on safety measures. There are, for example, no lines that have to be checked for leaks on a regular basis.
 
The process is already proving its effectiveness in areas such as the automobile sector, where, for instance, it is used for cleaning carbon parts prior to painting.
The engineers at Bausch+Ströbel were quick to identify the potential applications of this process in the pharmaceuticals sector, too.
 
Pack Expo Technology Excellence Award in der Kategorie Pharmaceuticals/Medical Device
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More possibilities in small batch production


Bausch+Ströbel has built small, semi-automatic machines for small-batch production – mostly in laboratories – right from the start. They can be used to process bottles, vials, cartridges, syringes and test tubes. Their special feature is that they employ the same filling and sealing technologies as high-speed machines.

All adjustments can be carried out on a touch screen. Parameters such as speed, position or filling quantity can also be stored and filed there as so-called recipes. All movements are servomotor controlled. The optional filling needle movement allows bottom-up filling with the needle immersed thereby ensuring gentle handling of the product.

By the use of scales, an in-process control of up to 100 % is possible, with automatic feedback adjustment of the dose during production. Batch reports can be saved and printed using the printer supplied together with the machine equipment.

It is the L-shaped design that all new semi-automatic machines have in common. They are not only easy to clean but can also be used in an isolator as they easily withstand the sterilization process inside the isolator. Each individual machine can also be operated with gloves.

This allows interesting combinations with the modular system VarioSys . The VarioSys is a small, space-saving system which can handle different products and batches in an isolator in quick succession due to short changeover times.